Serum calprotectin levels correlate with biochemical and histological markers of disease activity in TNBS colitis
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Correlation between Serum Levels of Calprotectin with Disease Activity in Rheumatoid Arthritis Patients
Background and Objective: Rheumatoid arthritis (RA) is an autoimmune disease defined by chronic synovitis and progressive joint destruction. This study investigated calprotectin as a serological marker in the hope of establishing an adequate means of diagnosing RA and following up on patients. Materials and Methods: This cross-sectional study included 32 RA patients who were referred to the rh...
متن کاملIncreased fecal calprotectin levels in Crohn’s disease correlate with elevated serum Th1- and Th17-associated cytokines
BACKGROUND Patient-reported symptoms and endoscopic disease activity do not correlate well in Crohn's disease (CD). This warrants the need for reliable biomarkers to early detect active intestinal inflammation. Currently, the fecal calprotectin level is the most commonly used biomarker for inflammatory activity in CD. However, the diagnostic accuracy of the fecal calprotectin level is not fully...
متن کاملSerum Renalase Levels Correlate with Disease Activity in Lupus Nephritis
INTRODUCTION Lupus nephritis (LN) is among the most serious complications of systemic lupus erythematosus (SLE), which causes significant morbidity and mortality. Renalase is a novel, kidney-secreted cytokine-like protein that promotes cell survival. Here, we aimed to investigate the relationship of serum renalase levels with LN and its role in the disease progression of LN. METHODS For this ...
متن کاملSerum levels of soluble receptor for advanced glycation endproducts (sRAGE) are higher in ulcerative colitis and correlate with disease activity.
UNLABELLED Interaction of the receptor for advanced glycation endproducts (RAGE) with its ligands results in expression of inflammatory mediators, activation of NF-κB, and induction of oxidative stress, all of which have been implicated in the pathogenesis of inflammatory bowel diseases (IBD). Soluble receptor for advanced glycation endproducts (sRAGE) has recently emerged as a reliable biomark...
متن کاملFecal Calprotectin and Clinical Disease Activity in Pediatric Ulcerative Colitis
Objective. To explore fecal calprotectin levels in pediatric ulcerative colitis (UC) in relation with the validated clinical activity index PUCAI. Methods. This study included all 37 children (median age 14 years) with UC who had calprotectin measured (PhiCal ELISA Test) by the time of PUCAI assessment at the Children's Hospital of Helsinki in a total of 62 visits. Calprotectin values <100 μ g...
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ژورنال
عنوان ژورنال: Cellular Immunology
سال: 2013
ISSN: 0008-8749
DOI: 10.1016/j.cellimm.2013.04.004